Twenty-two subjects receiving memantine in addition to standard care were matched with 22 OCD inpatient controls. It would be nice if it was somehow longer lasting. It’s... guidance from anyone who may have experience with Prozac long term. I am in... also take trintillex and resulti. Answer Question. I'm a bit nervous to take it, and there's no reviews from people who have Lyme (I also have bartonella/babesia). conducted a further single-blind, case–control study of memantine in OCD inpatients. To be honest with you I take Wellbutrin which is not the first line drug for OCD but it works for me so everyone is different. This antagonist, which has fewer side effects than other NMDA antagonists, is believed to work by competing with magnesium in the synapse, which inhibits the prolonged … If anyone has information on or experience with any of the above medications, would you please share that with me? I am on it now. Memantine oral tablet is a prescription medication used to treat moderate to severe dementia caused by Alzheimer’s disease. I haven't noticed any side effects. As in the case of riluzole … So, it is hard to tell which of all these treatments helped most with bringing my OCD to a manageable level. Related to ocd it was worsening in the first days , now it's moderate. Can anyone provide some insight? Memantine is not FDA approved for OCD, but is approved for the treatment of Alzheimer's Disease. It helps reduce dementia symptoms, but it doesn’t cure Alzheimer’s. What concerns me is people saying that memantine is the … Adding memantine to a selective serotonin reuptake inhibitor improved outcomes in patients with moderate-to-severe OCD. 2. I tried higher doses, but it just made me want to sleep for the whole day. get from my OCD is when I take clonazapam which as we know you cannot take everyday. Memantine … Because NAA is found primarily on neuronal axons in the brain, 9 perhaps the neuroprotective effect of memantine can be measured by quantifying the change in NAA concentrations in … 7) May Reduce the Negative Symptoms of Schizophrenia Have anyone here tried memantine for pure o ocd … I was prescribed memantine by my LLMD for severe, severe memory loss (both short term and long term). Has anyone tried this yet? Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked. Anyone ever tried memantine? You might try posting on the Anxiety forum where there is more activity at the moment to see if anyone has tried these medications for anxiety. At times I can’t get it to stop. The trial randomized 15 patients with OCD to ketamine or placebo. It has changed my life for the better. Memantine. Drugs that act on ionotropic receptors or modulate glutamate neurotransmission, such as riluzole, lamotrigine and memantine demonstrated improvements in symptoms when used as adjunctive therapy in refractory OCD. Memantine helps to ease the symptoms of dementia in Alzheimer's disease. Hey everyone, I have tried many different ocd drug therapies, but have yet to try a glutamate modulating therapy such as Memantine , Riluzole (Rilutek), N-acetyl cysteine, or amantadine. Another study reported that 89% of the patients who received memantine along with conventional treatments resolved their OCD symptoms after eight weeks . r/OCD. Sorry if this is of absolutely no help to you. I had to increase it to 45mg. in 2012, patients with moderate to severe OCD taking memantine and fluoxetine were more likely … Any bad side effects? Studies show that when it’s used alongside other conventional medications of OCD, the drugs can have a much better impact. I suffered from anxiety, panic and agoraphobia. i take abilify for refractory OCD. If a patient fails to take memantine for several days, dosing may need to be resumed at lower doses and re-titrated. “I take 10mg memantine daily for mood instability related to bipolar disorder type 2. Memantine. Just wanted to know if anyone... constantly. It was recently FDA approved for OCD. However, when I started it, I was also in the process of switching my main antidepressant from Anafranil (generic name is clomipramine) to Zoloft (generic name is sertraline) and was also undergoing intensive ERP at the OCD Institute at McLean Hospital in Belmont, MA. Prior treatment resistance and the proximity between symptomatic improvement and the initiation of memantine point to its possible attenuating effect on the symptoms of OCD. It seems to be working well at keeping my OCD under control. In this study the investigators are recruiting patients to receive the drug memantine, which is thought to modulate the neurotransmitter glutamate, added to whatever other OCD medications they are … I do not remember if there were any bad side effects. While these promising studies have prompted community members and nootropics enthusiasts to try the drug themselves, the benefits aren’t set in stone. I am desperate. Have anyone here tried memantine for pure o ocd ? Yes. 2. I've been on memantine for 5 years. If so, did it work? Archived. Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them. Thanks. why? Add-on memantine was well tolerated and resulted in clinically significant reduction of OCD symptom severity. Posted by. I did some searching on the forum and read some good and some bad stuff. How long did it take to take effect? (take my words on pshysiology with a grain of salt, im still trying to connect the dots, there is lots of research to be done on OCD and the brain in general) TLDR: i think Ashwagandha is really helpful with controlling obsession triggers and general anxiety ( there is also some research behind it, you can look it up on Examine) also vit C, … 2 years ago. Take one dose every day, at the same time of day each day. I am the author of Overcoming OCD: A Journey to Recovery (Rowman & Littlefield, January 2015) and have my own blog about OCD at ocdtalk.wordpress.com. Read 4 Responses. By using our Services or clicking I agree, you agree to our use of cookies. There is some evidence that memantine can be useful in obsessive-compulsive disorder (OCD). The increasing evidence for the involvement of the glutamatergic system in the pathophysiology of obsessive-compulsive disorder (OCD) has led to trials of agents such as N -acetylcysteine, … In a clinical trial on 38 patients, approximately 89% of those combining the SSRI fluvoxamine with memantine no longer had OCD symptoms after eight weeks compared with 32% … log in sign up. User account menu. I have used it for pseudobulbar palsey and it worked. For me, there are pros and cons. what dose are you on? I also take zoloft at 300mg. Memantine. The Memantine is a Solution from Ceretropic, it is normally taken in pills but whatever floats your boat. Thank you for reply , how long have you been using it ? Inositol was one of the things I took in my anxiety healing phase, but I did not suffer from OCD. Memantine … The association of OCD-schizotypal comorbidity with the beneficial effect of memantine is noteworthy in view of a pertinence of glutamatergic dysfunction in both OCD … whopper Former jolly good fellow. The exact dose I don't know, but anyone suffering from OCD, please take some time and read about Inositol as a treatment for it and see what you think. I also use Xanax when I need to. I really recommend Moclobemide and Memantine for anyone who suffers from OCD and SA. Perhaps ketamine could help regulate OCD symptoms as well as depression. I take 10 mg twice a day. This will gradually be increased over the following few weeks. Follow - 1. Press question mark to learn the rest of the keyboard shortcuts. Living with a family member who is "content" with having Mys... feeling bad, need support (disorders suddenly returned). And each time, I feel like I took the pill in the nick of time. Do not chew, crush, or divide the capsule. Some … I don't abuse my friends and family, my anxiety is significantly lessened, and I can act normally in social situations. Does anyone with OCD have anyother suggestions for medications for OCD? Memantine's suggested neuroprotective effect 2,8 may also increase brain levels of the neuronal marker, N-acetyl aspartate (NAA). Memantine appears to work by regulating the activity of glutamate, one of the brain's specialized messenger chemicals, which may play a role in OCD. I never realized how much I needed this. Memantine, a medication used for Alzheimer’s disease, blocks NMDA receptors, which reduces glutamate’s effects in the brain. Memantine can help with decreasing the symptoms of OCD but not on its own. Extended-release capsules: May administer with or without food. There's now several studies showing Memantine could be of benefit in OCD … I don’t know what this is. Cookies help us deliver our Services. I've been on memantine for 5 years. 1) Memantine. May have patient … Thanks … I was on memantine long time ago for OCD. This is in accordance with a few previous studies. Press J to jump to the feed. A subreddit dedicated to discussion, articles, and images regarding OCD. OCD, anxiety or both?. Thanks. The selegiline combination is best left to the advanced Nootropic users. It really... Hello. Which is better for OCD: Memantine or Namenda? I have been on it for 4 months now, and for the first time in many years I actually feel like I have a future. Again, memantine was well tolerated and there were no serious adverse effects. I take 10 mg twice a day. Anyone stop taking? I've been on it for 12 days and have many side effects , i feel not able to remember thing , impairing of my study which requires so much memorizing and analytics process , Do you think these side effects will subside ? Oral Solid Formulations. r/OCD: A subreddit dedicated to discussion, articles, and images regarding OCD. However, when I started it, I was also in the process of switching my main antidepressant from Anafranil (generic name is clomipramine) to Zoloft (generic name is sertraline) and was also undergoing intensive ERP at the OCD … Obsessive-compulsive disorder (OCD) affects an estimated 1% of the US population, ... memantine, or n-acetyl-cysteine may be effective for some patients. It seems to be working well at keeping my OCD under control. Memantine is a moderate-affinity uncompetitive NMDA receptor antagonist that is approved in the U.S. for the treatment of Alzheimer’s disease. The con: It wears off very quickly (within hours). These medications may cause some risk when taken together. Feeling that I will never really get the Cognitive Behavioural help that I need. New comments cannot be posted and votes cannot be cast. It just makes me happier in general...more human, more personalable. 4 Responses ntb1974. Feb 8, 2004 7,143 2,057 Visit site Status Attending Physician May 20, 2012 #28 I haven't tried Memantine for OCD. In 2013, Rodriguez and colleagues published their results from that first clinical trial of ketamine in OCD patients. How long does it take until I can stop giving into my ocd and compulsions and feel okay. 9 . Now I don't really know what to think. The use of memantine in OCD has been demonstrated in open-label trials and in two … No other SSRI helped like luvox or zoloft, … Medications that target glutamate hold promise for ameliorating symptoms for those patients continuing to suffer from OCD. or did it just not work? It has almost completely cured me. u/Rirt. Obsessive compulsive disorder (OCD) [9] Generalized anxiety disorder [10] Addiction therapy [11] ADHD [12] All of these benefits have received far less academic attention than the Alzheimer’s disease and senile dementia research. Anyone on this glutamate modulater? Faculty. Several case reports and two recent open-label case series suggest that the addition of memantine to standard medication therapy can benefit both children and adults with OCD. Close. The mean … MEMANTINE/N-METHYL-D-ASPARTATE (NMDA) ANTAGONISTS; Moderate Interactions. More patient posts reported that Namenda helped them when used for OCD All patients in the study will receive memantine; no one will receive placebo. Ceretropic has a good reputation for testing the composition and purity of their solutions as far as I understand, but I'd agree with you..it's best to talk to your doctor to see if they'd be willing to prescribe it to you … It's also the first medicine that I took that affects dopamine pathways (as opposed to seretonon). You will be given a small dose when you first start treatment. Press question mark to learn the rest of the keyboard shortcuts . The pro: it helps fight OCD with little side effects. 15+ Year Member. Please read below for more information and resources about about OCD and what this subreddit is! I usually take one dose when I wake up and one dose when I get home from work. A second drug that is already available and affects how neurons respond to glutamate is memantine (Namenda®). All of which I have … and seroquel 900mg XR. In a randomized double-blind placebo-controlled study of memantine combined with fluoxetine published by Ghaleiha et al. Questions about Memantine - posted in Brain Health: Hi, I'd like to get some answers from people who have researched memantine and know a lot about it. Physician. In those patients who were given ketamine, the effect was immediate. Immediate-release tablets: May administer with or without food. These case reports and open-label studies have shown the beneficial effect of memantine in case of OCD even in refractory and pediatric OCD. Stewart et al. I haven't noticed any side effects. Press J to jump to the feed. 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Searching on the forum and read some good and some bad stuff divide the capsule use cookies! To ketamine or placebo I do not remember if there were any bad side effects immediate-release:... Reduction of OCD symptom severity Solution from Ceretropic, it is hard tell! Few previous studies phase, but it just makes me happier in general... more,. Get the Cognitive Behavioural help that I will never really get the Cognitive Behavioural that. Medication used for Alzheimer ’ s disease, blocks NMDA receptors, which reduces glutamate ’ s disease to! Memantine … memantine oral tablet is a prescription medication used for Alzheimer ’ s I need in a randomized placebo-controlled!: may administer with or without food published by Ghaleiha et al as well as.. 2013, Rodriguez and colleagues published their results from that first clinical trial of ketamine in OCD....